Chloride
Chloride is a negatively charged molecule known as an electrolyte. It works with other electrolytes, such as potassium, salt (sodium), and carbon dioxide (CO2), to help keep the proper balance of body fluids and maintain the body´s acid-base balance.
A test can be done to measure the amount of this mineral in a urine sample.
Purpose of the Test
Your doctor may order this test if you have signs of a disturbance in your body´s fluid level or acid-base balance. It may be used to help determine the causes of hypokalemia, and to aid in the diagnosis of renal tubular acidosis.
How to Prepare for the Test
The health care provider will instruct you, if necessary, to discontinue drugs that may interfere with the chloride test.
Drugs that may decrease the level of this mineral in the urine include:
- Acetazolamide
- Nonsteroidal anti-inflammatory drugs
Drugs that may increase the level of this mineral in the urine include:
- Corticosteroids
- Loop diuretics
- Thiazide diuretics
Normal Results
The normal range is 20 to 250 milliequivalents per day (mEq/day). This range depends greatly on your salt intake and your level of hydration.Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
What Abnormal Results Mean
Increased urine chloride levels may be caused by:
- Adrenocortical insufficiency
- Increased salt intake
- Inflammation of the kidney that results in salt loss
- Production of an unusually large amount of urine
Decreased urine levels of this mineral may be due to:
- Cushing syndrome
- Decreased salt intake
- Fluid loss that occurs with diarrhea, vomiting, sweating, and gastric suction
- Salt retention