What Is Sarcoidosis?
This disease can occur in almost any part of your body, although it usually affects some organs more than others. It usually starts in one of two places:
- Lungs
- Lymph nodes, especially the lymph nodes in your chest cavity.
Sarcoidosis also often affects your:
- Skin
- Eyes
- Liver.
Less often, this disease affects your:
- Spleen
- Brain
- Nerves
- Heart
- Tear glands
- Salivary glands
- Bones and joints.
Rarely, does this disease affect other organs, including your:
- Thyroid gland
- Breasts
- Kidneys
- Reproductive organs.
This disease almost always occurs in more than one organ at a time.
Sarcoidosis has an active and a nonactive phase:
- In the active phase, the granulomas form and grow. In this phase, symptoms can develop, and scar tissue can form in the organs where the granulomas occur.
- In the nonactive phase, the inflammation goes down, and the granulomas stay the same size or shrink. But the scars may remain and cause symptoms.
The course of the disease varies greatly among people.
- In many people, this disease is mild. The inflammation that causes the granulomas may get better on its own. The granulomas may stop growing or shrink. Symptoms may go away within a few years.
- In some people, the inflammation remains but doesn't get worse. You may also have symptoms or flare-ups and need treatment every now and then.
- In other people, this disease slowly gets worse over the years and can cause permanent organ damage. Although treatment can help, this disease may leave scar tissue in the lungs, skin, eyes, or other organs. The scar tissue can affect how the organs work. Treatment usually does not affect scar tissue.
Changes in sarcoidosis usually occur slowly (e.g., over months). This disease does not usually cause sudden illness. However, some symptoms may occur suddenly. They include:
- Disturbed heart rhythms
- Arthritis in the ankles
- Eye symptoms.
In some serious cases in which vital organs are affected, sarcoidosis can result in death.
Sarcoidosis was identified in the late 1860s. Since then, scientists have developed better tests to diagnose it and made advances in treating it.
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